Probiotics for Psoriasis - Helping to Calm Inflammation

Psoriasis, a prevalent skin condition, is often associated with inflammation and immune system  imbalances. Research indicates that probiotics could be a natural remedy to combat inflammation and  support skin health. These beneficial bacteria, found in supplements or certain foods, aid in balancing  gut microbes. This balance is crucial for maintaining overall immunity.

Various studies have explored probiotic treatment for its potential benefits in managing psoriasis, highlighting how probiotics can influence gut microbiota to reduce inflammation and improve skin symptoms.

A 12-week clinical trial with 63 participants demonstrated the efficacy of probiotics in reducing  inflammation. Those receiving probiotics saw a significant decrease in TNFα and IL-6 levels. In contrast, the control group experienced no such reduction. Probiotics like Bifidobacterium infantis 35624 and  Lactobacillus sporogenes have shown potential in reducing skin inflammation and enhancing psoriasis  treatment outcomes.

At Australian Psoriasis and Eczema Supplies, we focus on evidencebased approaches. Research  indicates that specific probiotic strains, such as Bacillus indicus and Saccharomyces boulardii, may aid inrestoring gut health. A healthy gut microbiome is essential for the gutskin axis, influencing skin  inflammation and immune responses related to psoriasis.

Probiotics function by regulating inflammatory cytokines. For instance, a study found that IL-10 levels increased in probiotic users, enhancing anti-inflammatory activity. This supports research that probiotics  can improve skin health by addressing gut dysbiosis, a factor contributing to psoriasis flare-ups.

Understanding Psoriasis, Psoriatic Arthritis, and Their Inflammatory Nature

Psoriasis is an autoimmune condition where the immune system attacks healthy skin cells. This triggers  inflammation and rapid skin cell growth. Inflammation causing bacteria in the gut can exacerbate this immune response, leading to thick, red plaques and silvery scales typical of psoriasis symptoms. 

Inflammatory cytokines like TNF-α and IL-17 drive this overactive immune response.

Severe psoriasis can evolve into pustular or chronic plaque forms. Disease severity varies based on genetics and environment. This condition is complex, influenced by both genetic predisposition and  environmental factors.

What Causes Psoriasis Flare-ups?

• Stress or infections can ignite flare-ups.

• Certain medications, like beta-blockers or antimalarials, may worsen symptoms.

• Certain foods high in sugar or processed ingredients might trigger inflammation.

Psoriasis flare-ups are not isolated. They are linked to systemic inflammation, increasing the risk of psoriatic arthritis,  inflammatory bowel disease, and cardiovascular disease. Proinflammatory cytokines like IL-23 and IL-22fuel host inflammatory processes. This creates a cycle of  inflammation affecting the skin and organs.

Australian Psoriasis and Eczema Supplies emphasizes the importance of managing triggers and  understanding these connections. By addressing the root causes, from diet to immune dysregulation,  individuals can take proactive steps. Probiotics may play a role in modulating these pathways, as  emerging research suggests.

The Gut-Skin Axis: How Your Digestive Health Affects Your Skin

The gut-skin axis reveals a profound connection between gut microbiota and skin health. Studies  indicate that psoriasis patients with altered gut microbiota experience heightened skin inflammation. A  balanced gut microbiome is crucial, as it produces short chain fatty acids (SCFAs). These compounds  are anti-inflammatory and fortify gut barriers.

For those with psoriasis, an imbalance in gut bacteria can trigger flareups. This imbalance disrupts the  protective mechanisms that keep inflammation at bay.

The Science Behind the Gut-Skin Connection

Several pathways link gut and skin health:

• Immune regulation: Gut bacteria influence T cells, which control inflammation.

• SCFA production: Beneficial bacteria create anti-inflammatory compounds like butyrate.

• Pathogen invasion prevention: A healthy microbiome blocks harmful bacteria from entering the  bloodstream.

Factor	Healthy Individuals	Psoriasis Patients
Microbiome Diversity	High bacterial diversity	Reduced diversity
Beneficial Bacteria	Higher levels (e.g., Lactobacillus)	Lower levels
Inflammatory Bacteria	Lower levels	Higher levels

Oral administration of probiotic bacteria aims to restore balance. A systematic review underscores their benefits in reducing psoriasis severity by enhancing gut health. Australian Psoriasis and Eczema  Supplies draws on these insights, promoting holistic care that encompasses both gut and skin health.

Probiotics for Psoriasis: What the Research Shows

Research on probiotics and psoriasis shows mixed but promising results. Scientists have looked into how Lactobacillus and Bifidobacterium might help alleviate symptoms. A 2012 case study noted a woman with pustular psoriasis experienced a decrease in lesions after consuming Lactobacillus. This study suggested that probiotics could be a useful supplementary treatment.

Recent clinical trials have provided further insights. In a 2013 double-blind trial, 50 participants received Bifidobacterium infantis 35624. The group taking the probiotic showed lower inflammation markers than the placebo group. Statistical analyses confirmed that probiotic users had reduced C-reactive protein (CRP). This study ensured unbiased results by comparing two groups. Additionally, the probiotic group compared to the placebo group showed significant improvements in psoriasis disease activity and quality of life metrics after an 8-week treatment course.

Study	Probiotic Used	Key Outcome
2012 Case Study	Lactobacillus	Lesion reduction in 2 weeks
2013 RCT	B. infantis 35624	Lower CRP and IL-6 in probiotic group
2015 Meta-Analysis	Multiple strains	Probiotics reduced CRP by 2.36 mg/L vs placebo

Research indicates that probiotics may help improve PASI scores, a measure of psoriasis severity. Yet, the effectiveness varies. Some trials show modest benefits, while others find no difference between probiotic and control groups. Experts stress the need for larger studies and longer follow-ups to solidify these findings.

Previous studies also underscore challenges. While probiotics are generally safe, it’s crucial to account for placebo effects in statistical analyses. Australian Psoriasis and Eczema Supplies advocates for making informed choices based on emerging evidence. Ongoing clinical trials aim to better understand the role of probiotics in managing this chronic condition.

Key Probiotic Strains and Beneficial Bacteria That Show Promise for Psoriasis Management

At the core of emerging treatments for psoriasis are effective strains of probiotic bacteria. Lactobacillus rhamnosus and Bifidobacterium infantis stand out in clinical and preclinical research. They show promise in reducing inflammation and enhancing skin health through specific mechanisms.

Lactobacillus Rhamnosus and Its Anti-inflammatory Properties

A 2012 case study demonstrated the efficacy of Lactobacillus rhamnosus in treating pustular psoriasis. After just two weeks, the patient's skin lesions significantly diminished. This strain's benefits are thought to stem from its ability to modulate cytokines, which are key drivers of psoriasis inflammation.

In 2013, a study on Bifidobacterium infantis 35624 revealed promising results. Participants experienced a decrease in inflammatory biomarkers such as CRP, TNF-α, and IL-6. The probiotic group showed a  66.7% improvement in PASI 75, outperforming the placebo. This strain's potential to enhance regulatory T cells may underpin its anti-inflammatory effects.

Strain	Study Year	Key Findings
Lactobacillus rhamnosus	2012	Reduced skin lesions in a case study; cytokine modulation observed
Bifidobacterium infantis 35624	2013/2019	Cut inflammatory biomarkers; PASI 75 improvement in 66.7% of patients
Lactobacillus pentosus GMNL-77	Preclinical	Reduced erythema and scaling in mice studies

Combining probiotic lactobacillus strains with prebiotics, such as fructooligosaccharides, enhances their therapeutic potential. This combination boosts short chain fatty acid production. Adjuvant therapy with  probiotic mixes could synergize with current treatments. Australian Psoriasis and Eczema Supplies  provides products with these evidence backed bacterial species. They aim to support skin health  through targeted probiotic groups.

How Probiotics Help Reduce Psoriasis Severity and Symptoms

Probiotics play a crucial role in managing psoriasis by modulating the immune system. They aid in  balancing immune cells, such as T lymphocytes, which are pivotal in controlling inflammation. This  balance helps in reducing the levels of proinflammatory cytokines like TNF-α and IL-17. These  cytokines are major contributors to psoriasis lesions and skin irritation. By lowering their levels, probiotics can significantly reduce psoriasis severity and improve symptoms over time.

Studies have demonstrated the efficacy of probiotics in reducing psoriasis severity. For instance:

• Probiotic groups in studies saw average PASI score improvements of 1.83 standard deviations.

• CRP and TNF-α levels dropped significantly in psoriasis patients, reducing inflammation.

• A 2012 case study reported reduced psoriasis lesions within two weeks using Lactobacillus.

• Bifidobacterium infantis 35624 lessened inflammation biomarkers in a 2013 trial.

Probiotic Strain	Effect	Study Year
Lactobacillus	Reduced lesion size and redness	2012
Bifidobacterium infantis 35624	Lowered TNF-α and CRP levels	2013

Regular use of probiotics can lead to symptom improvement in 4-8 weeks. Results may vary, but  combining probiotics with other treatments can enhance skin healing  and reduce flareups. Australian Psoriasis and Eczema Supplies offers probiotic options tailored to  support  gut-skin health, aiding in long-term management of active psoriasis.

Incorporating Probiotics Into Your Psoriasis Management Plan

Adding probiotics to your daily routine can be a natural step in managing psoriasis. Start by  incorporating probiotic rich foods like yogurt, kefir, or sauerkraut into your diet. These items are  packed with beneficial bacteria that aid in gut health and may help alleviate symptoms over time. For those seeking a more concentrated option, probiotic supplements are available. They are formulated to  enhance the probiotic group in your system.

Probiotic-Rich Foods	Probiotic Supplements
Yogurt (unsweetened)	Lactobacillus acidophilus
Kimchi	Bifidobacterium lactis
Kombucha	Multistrain capsules (1–10 billion CFU)
Sourdough bread	Strains like Lactobacillus plantarum

Combining probiotics with traditional treatments like topical creams or medications can offer a balanced approach. Always consult your doctor before adding probiotics to ensure they are safe to use with your current therapies. Regular intake of these beneficial bacteria may lead to improved skin health over time.

• Include fermented foods like tempeh or miso in meals.

• Choose supplements verified for live bacteria counts and storage stability.

• Track symptom changes alongside gut health improvements.

Australian Psoriasis and Eczema Supplies provides practical advice on integrating probiotics into your  skincare routine. Whether through supplements or dietary choices, a consistent routine is key to long-term psoriasis management.

Conclusion: A Balanced Approach to Managing Psoriasis with Australian Psoriasis and Eczema Supplies

Managing psoriasis demands a balanced strategy, blending traditional treatments with complementary  options like probiotics. Australian Psoriasis and eczema supplies provides a variety of products to support this holistic approach. Probiotics, such as beneficial bacteria strains like Lactobacillus, may help reduce inflammation and enhance skin health. They do this by addressing gut imbalances that can trigger  flare-ups.

Research indicates that probiotics like SEL001 can lower inflammatory markers like IL-17A and IL-23,  similar to corticosteroids. This aligns with studies showing probiotics' role in modulating the gut-skin  axis. Yet, it's crucial to remember that probiotics alone are not a cure-all. Continue using prescribed  medications and topical treatments as advised by healthcare professionals.

Patients should stick to using moisturisers and prescribed ointments while exploring the benefits of  probiotics. Australian Psoriasis and Eczema Supplies offers resources to help individuals incorporate these strategies without disrupting their current treatment plans. It's important to note that individual  responses to probiotics can vary. Always consult a doctor before adding probiotics to your skincare  routine.

By combining probiotics with established psoriasis treatments, individuals can tackle inflammation from different angles. Australian Psoriasis and Eczema Supplies is dedicated to providing evidence-based solutions for skin health. Visit us to discover products that reflect the latest insights on gut-skin wellness and psoriasis management.

FAQ

What is psoriasis and how does it affect the skin?

Psoriasis is a chronic autoimmune skin condition characterized by the rapid growth of skin cells, leading to thick, red, scaly patches known as skin lesions. Affecting approximately 2-3% of the global population, psoriasis is more prevalent in developed countries. This condition can cause significant discomfort, pain, and emotional distress, impacting a person’s quality of life. The exact cause of psoriasis remains unknown, but it is believed to result from a combination of genetic, environmental, and immune system factors. Psoriasis manifests in several forms, including plaque psoriasis, guttate psoriasis, inverse psoriasis, and pustular psoriasis, each with its unique clinical symptoms and triggers.

How can probiotics help with psoriasis symptoms?

Probiotics, which are live beneficial bacteria, have shown promise in managing psoriasis symptoms by naturally reducing inflammation and improving gut health. These beneficial bacteria can stimulate T cells, crucial components of the immune system, to help regulate immune responses and decrease skin inflammation. Specific strains like Lactobacillus and Bifidobacterium are particularly effective in balancing the gut microbiome, which in turn can positively impact the gut-skin axis. This connection between gut health and skin health underscores the potential of probiotics to alleviate psoriasis symptoms by addressing underlying inflammation and immune dysregulation.

What are some common triggers for psoriasis flare-ups?

Psoriasis flare-ups can be triggered by a variety of factors, making it essential for individuals to identify and manage their specific triggers. Common triggers include stress, smoking, and certain medications such as beta-blockers and antimalarials. Environmental factors like heat, certain foods, perfumes, and chemicals can also provoke flare-ups. Keeping a detailed log of triggers and symptoms can help identify patterns and manage flare-ups more effectively. Adhering to a consistent psoriasis treatment regimen, including topical treatments and oral medications, and maintaining well-lubricated and clean skin are crucial steps in managing this condition.

Which probiotic strains are beneficial for psoriasis?

Research indicates that certain probiotic strains can be particularly beneficial for managing psoriasis. Strains such as Lactobacillus paracasei, Lactobacillus salivarius, Bifidobacterium infantis, and Lactobacillus rhamnosus have shown potential in reducing inflammation and improving clinical symptoms in psoriasis patients. These strains work by modulating the immune system and enhancing the balance of gut bacteria, which can lead to reduced skin inflammation and improved overall skin health. However, further research is needed to fully understand the effectiveness and mechanisms of these probiotics in psoriasis treatment.

How do probiotics affect inflammatory cytokines?

Probiotics can significantly impact inflammatory cytokines, which are key players in the development and progression of psoriasis. These beneficial bacteria can reduce the production and release of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-8. They achieve this by suppressing the activation of NF-κB, a transcription factor involved in inflammation and immune responses. Additionally, probiotics can upregulate the expression of anti-inflammatory cytokines like IL-10, further helping to reduce inflammation and improve psoriasis symptoms. This dual action on inflammatory and anti-inflammatory pathways highlights the potential of probiotics as a complementary approach in psoriasis management.

Can I take probiotics alongside traditional psoriasis treatments?

Yes, probiotics can be safely taken alongside traditional psoriasis treatments. In fact, they may serve as a valuable adjunct to conventional therapies. Probiotics can help reduce inflammation and improve symptoms, complementing the effects of traditional treatments such as topical creams, oral medications, and biologics. However, it is essential to consult with a healthcare provider before adding probiotics to your psoriasis management plan. This ensures that the probiotics are safe to use with your current treatments and that you receive personalized advice tailored to your specific condition and needs.

What is psoriasis and how does it affect the skin?

Psoriasis is an autoimmune condition that causes red, scaly patches on the skin. It happens when skin  cells grow too fast and the immune system overreacts. This leads to inflammation and skin lesions.

How can probiotics help with psoriasis symptoms?

Probiotics may aid in managing psoriasis by improving gut health. They help reduce inflammation and  modulate immune responses. This can calm skin inflammation and improve symptoms.

What are some common triggers for psoriasis flare-ups?

Stress, certain medications, environmental factors, and dietary choices can trigger psoriasis flare-ups. These factors contribute to inflammation and worsen symptoms.

Which probiotic strains are beneficial for psoriasis?

Strains like Lactobacillus rhamnosus and Bifidobacterium infantis are beneficial for managing psoriasis.  They have anti-inflammatory properties and can modulate immune responses.

How do probiotics affect inflammatory cytokines?

Probiotics can regulate inflammatory cytokines such as TNF-α, IL-17, and IL-23. By reducing these cytokines, they may decrease inflammation and improve psoriasis symptoms.

Can I take probiotics alongside traditional psoriasis treatments?

Yes, probiotics can be used alongside traditional treatments. They provide additional support for gut  health and inflammation management without replacing conventional therapies.

What foods are rich in probiotics?

Foods rich in probiotics include yogurts, kefir, kombucha, sauerkraut, kimchi, tempeh, and fermented  cheeses. These can support gut health and potentially benefit psoriasis.

How long does it take to see improvements with probiotics?

Improvement times vary among individuals. But, consistent use of probiotics may lead to gradual  improvements in psoriasis symptoms over weeks to months.

Should I consult a healthcare provider before starting probiotics?

Yes, it’s recommended to consult with a healthcare provider before starting probiotics. This is crucial,  even if you're making changes to your psoriasis management plan.